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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM123
All Species:
13.94
Human Site:
Y198
Identified Species:
38.33
UniProt:
Q8N131
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N131
NP_443164.2
208
21531
Y198
Y
S
R
R
G
I
R
Y
R
T
I
D
E
H
D
Chimpanzee
Pan troglodytes
XP_001152921
208
21541
Y198
Y
S
R
R
G
I
R
Y
R
T
I
D
E
H
D
Rhesus Macaque
Macaca mulatta
XP_001097410
207
21407
Y197
Y
S
R
R
G
I
R
Y
R
T
I
D
E
H
D
Dog
Lupus familis
XP_854678
169
17566
R160
S
R
R
G
I
R
Y
R
T
I
D
E
H
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91Z22
195
20160
R186
S
R
R
G
I
R
Y
R
S
I
D
E
H
D
A
Rat
Rattus norvegicus
Q5HZB0
194
19965
R185
S
R
R
G
I
R
Y
R
S
I
D
E
H
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510060
301
32385
Y291
H
S
R
R
G
I
R
Y
R
T
I
D
E
H
D
Chicken
Gallus gallus
NP_001006279
185
18971
S176
I
G
C
K
T
Y
H
S
E
K
R
H
S
V
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648349
183
18923
A174
V
A
Y
K
F
Y
K
A
R
N
E
R
N
Y
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.2
41.8
N.A.
52.4
54.3
N.A.
32.2
33.1
N.A.
N.A.
N.A.
29.3
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
94.2
58.6
N.A.
64.4
65.8
N.A.
47.1
47.5
N.A.
N.A.
N.A.
44.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
6.6
6.6
N.A.
93.3
0
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
13.3
N.A.
100
6.6
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
0
12
0
0
0
0
0
0
34
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
34
45
0
34
45
% D
% Glu:
0
0
0
0
0
0
0
0
12
0
12
34
45
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
34
45
0
0
0
0
0
0
0
0
0
0
% G
% His:
12
0
0
0
0
0
12
0
0
0
0
12
34
45
12
% H
% Ile:
12
0
0
0
34
45
0
0
0
34
45
0
0
0
0
% I
% Lys:
0
0
0
23
0
0
12
0
0
12
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Q
% Arg:
0
34
78
45
0
34
45
34
56
0
12
12
0
0
0
% R
% Ser:
34
45
0
0
0
0
0
12
23
0
0
0
12
0
0
% S
% Thr:
0
0
0
0
12
0
0
0
12
45
0
0
0
0
0
% T
% Val:
12
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
34
0
12
0
0
23
34
45
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _